1. BMC Womens Health. 2023 Dec 1;23(1):641. doi: 10.1186/s12905-023-02733-1
Application an internet facilitation in a community-based cervical cancer screening project.
Du H(#)(1)(2)(3), Qu X(#)(2)(3), Wang G(1), Guo C(1), Wang Z(4), Min J(4), Liu
Z(1)(2)(3), Hu Q(1)(2)(3), Luo H(1), Wang C(1)(2)(3), Huang X(1)(2)(3), Chen
Y(1)(5), Wu B(1)(5), Belinson JL(6)(7), Wu R(8)(9)(10).
Author information:
(1)Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital,
No. 1120, Lianhua Road, Shenzhen, 518036, PR China.
(2)Institute of Obstetrics and Gynecology, Shenzhen PKU-HKUST Medical Center,
Shenzhen, PR China.
(3)Shenzhen Key Laboratory on Technology for Early Diagnosis of Major
Gynecologic Diseases, Shenzhen, PR China.
(4)Pinshan Renmin Hospital, Shenzhen, PR China.
(5)Shenzhen Medical Women’s Association, Shenzhen, PR China.
(6)Preventive Oncology International, Inc, Cleveland Heights, OH, USA.
(7)Women Health Institute, Cleveland Clinic, Cleveland, OH, USA.
(8)Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital,
No. 1120, Lianhua Road, Shenzhen, 518036, PR China. wurf100@126.com.
(9)Institute of Obstetrics and Gynecology, Shenzhen PKU-HKUST Medical Center,
Shenzhen, PR China. wurf100@126.com.
(10)Shenzhen Key Laboratory on Technology for Early Diagnosis of Major
Gynecologic Diseases, Shenzhen, PR China. wurf100@126.com.
(#)Contributed equally
OBJECTIVE: To evaluate the feasibility of an internet-facilitated community
model for cervical cancer screening using self-collected HPV testing as primary
screening.
METHOD: A population-based cervical cancer screening program was conducted in
the suburb of Shenzhen, China, from September 2014 to July 2017. Women with
25-60 years of age and no pregnancy were eligible for participation.
Participants could register for screening by logging in a website by themselves
or with the aids of local community workers. A unique barcode was issued to each
applicant upon successful registration. After registration, women could get
sampling kits from community screening site/study clinic, collect vaginal
samples privately or in group, and provide their sample for Hr-HPV tests on
Cobas4800 and SeqHPV assays. Testing reports were checkable through personal
account for all participant and phone calls were given to all women positive of
Hr-HPV. Participants positive of both or either the 2 assays were identified as
the positives. The positives could return the study clinic for triage or search
medical care in other clinics. Colposcopy directed or ramdom biopsies were
performed on all positives who returned to the study clinics.
RESULTS: A total of 10,792 community women registered for screening, among whom,
10,010 provided their vaginal samples for tests. 99.5% of the participants were
confirmed to have correct personal identifiable information and samples, and
98.9% of them got HPV testing results from both or either assays. No adverse
event was reported.
CONCLUSION: When self-collected HPV testing is used as the primary testing, the
internet-based data platform facilitates the screening in registration, data
collection, and data tracking, and increases the screening coverage.
Internet-facilitated community model is promising to cervical cancer control and
applicable in regions with variety of resources.
© 2023. The Author(s).
DOI: 10.1186/s12905-023-02733-1
PMCID: PMC10690986
PMID: 38041116 [Indexed for MEDLINE]
Conflict of interest statement: The authors declare no competing interests.